ABSOLUTE CONFIGURATION OF NORZOANTHAMINE, A PROMISING CANDIDATE FOR AN OSTEOPOROTIC DRUG

Abstract The absolute configuration of norzoanthamine ( 1 ) was determined to be 2 R 4 S , 6 S , 9 S , 10 R , 12 S , 13 R , 18 S , 21 S , and 22 S based on 1 H NMR spectral data of the MTPA esters of norzoamthamine derivatives. The possible biogenesis of zoanthamines is also proposed.