Urinary d-glucaric acid and serum hepatic enzyme levels in chronic alcoholics

Abstract Urinary d -glucaric acid (DGA) and the activities of gamma-glutamyl transferase (GGT) and other hepatic enzymes in serum were determined in 33 noncirrhotic male alcoholics who had continued to consume alcohol until at least 24 h prior to the taking of samples. DGA excretion was significantly greater in them than in a group of 30 healthy controls ( p r = 0.613, p r = 0.158, p ⋍ 0.4 ).