Clinical relevance of CD44 surface expression in advanced stage serous epithelial ovarian cancer: a prospective study.

Purpose Cluster of differentiation (CD) 44 is a cell surface receptor that correlates with the development of drug resistance in epithelial ovarian cancer (EOC). Here, we prospectively investigated the clinical impact of CD44 expression on the development of chemoresistance, and on disease-free and overall survival in EOC.