Rapid Evaluation of the Mechanism of Buchwald–Hartwig Amination and Aldol Reactions Using Intramolecular 13C Kinetic Isotope Effects

Victor Wambua,Jennifer S. Hirschi,Mathew J. Vetticatt

Rapid Evaluation of the Mechanism of Buchwald–Hartwig Amination and Aldol Reactions Using Intramolecular 13C Kinetic Isotope Effects

2020

Victor Wambua
Jennifer S. Hirschi
Mathew J. Vetticatt

A practical approach is introduced for the rapid determination of 13C kinetic isotope effects that utilizes a “designed” reactant with two identical reaction sites. The mechanism of the Buchwald–Ha...

Keywords:

Kinetic isotope effect
Computational chemistry
Catalysis
Reaction mechanism
Kinetic energy
Chemistry
Buchwald–Hartwig amination
Aldol reaction
Intramolecular force

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations