A simple visible spectrophotometric determination of Sumatriptan Succinate from pharmaceutical formulations

2011 
A simple, sensitive and cost effective visible spectrophotometric method was developed for the estimation of sumatriptan succinate in bulk and dosage forms. The method is based on the formation of purple red colored species with sodium nitroprussideacetaldehyde reagent exhibiting maximum absorption at 552 nm. Beer’s law obeyed in the concentration range of 4 - 20 μg/ml. commercially available tablets were analysed, the results obtained by the proposed method were in good agreement with the labeled amounts. These methods are reproducible with an accuracy of ±1 %.
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