Synthesis and antidepressant properties of novel 2-substituted 4,5-dihydro-1H-imidazole derivatives.

Mark P. Wentland,Denis M. Bailey,Alexander Ej,Castaldi Mj,Richard A. Ferrari,Dean R. Haubrich,Daniel Luttinger,Mark H. Perrone

Synthesis and antidepressant properties of novel 2-substituted 4,5-dihydro-1H-imidazole derivatives.

1987

Mark P. Wentland
Denis M. Bailey
Alexander Ej
Castaldi Mj
Richard A. Ferrari
Dean R. Haubrich
Daniel Luttinger
Mark H. Perrone

Synthese de R-methyl-2 imidazolines-2 par conversion nitrile→imidazoline de R-acetonitriles avec l'ethylenediamine et le trimethyl aluminium (R=indenyl-2, dihydro-3,4 naphtyl-2, naphtyl-2, tetrahydro-1,2,3,4 naphtyl-2). Etude biologique

Keywords:

Biochemistry
Imidazole
Aluminium
Organic chemistry
Biological activity
Napamezole
Ethylenediamine
Nitrile
Chemistry
Reuptake
Structure–activity relationship
P-Chloroamphetamine
Antagonist
Hydrochloride

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