Nanobiomaterials set to revolutionize drug-delivery systems for the treatment of diabetes: State-of-the-art

Abstract Diabetes can result when the accurate control of insulin levels fails in the body. As a result, insulin has been conventionally administered for the treatment of diabetes mainly through subcutaneous injection. There have been several attempts to administer insulin orally. However, the oral bioavailability of insulin is strictly limited, mainly by low permeability across biological membranes. Advances in biotechnology and nanotechnology have recently led to the discovery of several new approaches for the delivery of drugs. In this concept, nanobiomaterials have been shown to be promising candidates for oral insulin delivery. This chapter describes the recent advances and future prospects of using nanobiomaterials for innovative drug-delivery systems.