Covalent inhibition of ERK docking interactions

Tamer S. Kaoud,William H. Johnson,Andrea Piserchio,Nancy D. Ebelt,Mangalika Warthaka,Micael Cano,Rachel M. Sammons,Qiantao Wang,Pengyu Ren,Ranajeet Ghose,Kevin N. Dalby

Covalent inhibition of ERK docking interactions

2016

Tamer S. Kaoud
William H. Johnson
Andrea Piserchio
Nancy D. Ebelt
Mangalika Warthaka
Micael Cano
Rachel M. Sammons
Qiantao Wang
Pengyu Ren
Ranajeet Ghose
Kevin N. Dalby

The extracellular-regulated kinase (ERK) signaling pathway has been implicated in the regulation of several cellular functions, including cell differentiation, proliferation, and inflammatory respo...

Keywords:

Docking (dog)
Endocrinology
MAPK/ERK pathway
Internal medicine
Biology
Molecular biology
Covalent bond
Cellular differentiation
Signal transduction
Kinase
cellular functions
Cell biology

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