RING-CLOSING METATHESIS MEDIATED SYNTHESIS OF PYRROLIZIDINE AND QUINOLIZIDINE AZASUGARS

Abstract The synthesis of a novel perbenzylated pyrrolizidine starting from 2,3,5-tri- O -benzyl-arabinofuranose and based on a ring-closing metathesis (RCM) reaction is presented. In an analogous procedure, 2,3,5-tri- O -benzylxylopyranose was converted into a hitherto unprecedented quinolizidine azasugar.