Effect of Indacaterol/Glycopyrronium on Pulmonary Perfusion and Ventilation in Hyperinflated Patients with Chronic Obstructive Pulmonary Disease (CLAIM). A Double-Blind, Randomized, Crossover Trial

Jens Vogel-Claussen,Christian-Olaf Schönfeld,Till Kaireit,Andreas Voskrebenzev,Christoph Czerner,Julius Renne,Hanns-Christian Tillmann,Korbinian Berschneider,Simone Hiltl,Johann Bauersachs,Tobias Welte,Jens M. Hohlfeld

Effect of Indacaterol/Glycopyrronium on Pulmonary Perfusion and Ventilation in Hyperinflated Patients with Chronic Obstructive Pulmonary Disease (CLAIM). A Double-Blind, Randomized, Crossover Trial

2019

Jens Vogel-Claussen
Christian-Olaf Schönfeld
Till Kaireit
Andreas Voskrebenzev
Christoph Czerner
Julius Renne
Hanns-Christian Tillmann
Korbinian Berschneider
Simone Hiltl
Johann Bauersachs
Tobias Welte
Jens M. Hohlfeld

Rationale: In the CLAIM study, dual bronchodilation with indacaterol/glycopyrronium (IND/GLY) significantly reduced hyperinflation, which translated into improved cardiac function, measured by left...

Keywords:

Indacaterol
Anesthesia
Hyperinflation
Diabetes mellitus
Bronchodilation
Crossover study
Perfusion
Medicine
Cardiac function curve
Ventilation (architecture)
dual bronchodilation

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