Isolation, Structure Determination and Biological Activity of 25-Epi, $3{\alpha}-Carboxyacetylquercinic$ Acid in Daedalea dickinsii

In order to develope bioactive substances, dried fmit body of Daedalea dickinsii collected from Taeback mountain was extracted with ethanol, The compounds 1 and 2 were purified by solvent extraction, silica gel column chromatography and recrystallization from the ethanol extracts. Melting point, molecular weight and molar extinction coefficient of the compound 1 were estimated to be , 572 and 5,040 at 208 nm. The structure of this compound 1 has been elucidated to be 24S, 25S, acid using spectroscopic properties. This compound showed antibiotic activities against fungi, yeasts and bacteria and it also showed anticancer activity ) against Korean stomach cancer cell. Melting point, molecular weight and molar extinction coefficient of the compound 2 were estimated to be $233{\sim}235^ acid. The compound 2 showed different antibiotic activities with the compound 1.