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Dihydro GPR40 Modulators

2013 
A compound of Formula (I): Formula ** ** or a stereoisomer, a tautomer, a pharmaceutically acceptable salt or solvate thereof, wherein: R1 is independently phenyl substituted with 0-3 R6 or pyridinyl substituted with 0 -3 R6; R2 is, in each case independently halogen or C1-4 alkyl; R3 is independently selected from: CF3, 4-halo-Ph, 4-CN-Ph, 4-CO2 (C1-2 alkyl) -Ph, 2-halo-4-CN-Ph and pyrimidin-2-yl; R4 is independently C1-4 alkyl or cyclopropylmethyl; R5 is, in each case independently halogen; and R6, at each occurrence, is independently selected from: OH, halogen, CN, C1-4alkyl and C1-4alkoxy; and wherein the compound of Formula (I) can be isotopically labeled.
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