Anticonvulsive Properties of Cannabidiol in a Model of Generalized Seizure Are Transient Receptor Potential Vanilloid 1 Dependent

Royston A. Gray,Colin Stott,Nicholas A. Jones,Vincenzo Di Marzo,Benjamin J. Whalley

Anticonvulsive Properties of Cannabidiol in a Model of Generalized Seizure Are Transient Receptor Potential Vanilloid 1 Dependent

2019

Royston A. Gray
Colin Stott
Nicholas A. Jones
Vincenzo Di Marzo
Benjamin J. Whalley

Introduction: Highly purified cannabidiol (CBD) (approved as Epidiolex® in the United States) has demonstrated efficacy with an acceptable safety profile in patients with Lennox–Gastaut or Dravet s...

Keywords:

Mechanism of action
Generalized seizure
Cannabidiol
Epilepsy
Pharmacology
TRPV1
Transient receptor potential channel
Medicine
in patient
safety profile

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