Transcription factor KLF13 inhibits AKT activation and suppresses the growth of prostate carcinoma cells

BACKGROUND: Kruppel-like factor 13 (KLF13), a member of the KLF family, is involved in the development of immunological diseases and tumor progression. However, the expression patterns and potential functions of KLF13 in prostate carcinoma are still unknown. Here, we aimed to study the roles and mechanisms of KLF13 in prostate cancer.