Design, synthesis and bioactivity evaluation of Galf mimics as antitubercular agents
2016
Abstract A series of novel Gal f mimics has been synthesized and characterized by IR, 1 H NMR, 13 C NMR, mass spectral and element analysis. All the newly prepared compounds were screened for their antitubercular activities. Bioactivity assays manifested that most of Gal f mimics exhibited good antitubercular activities. Especially compound 4d and 4e displayed remarkable antitubercular efficacies, which were comparable to ethambutol.
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