안 합병증이 동반된 아토피 피부염의 임상적 특징

Background: Long-standing atopic dermatitis patients frequently predispose to ocular complications. The ectoderrnal origin of the epidermis and of many eye structures explain the fre~quent associations observed in atopic dermatitis. Objective: This study may help in evolving early diagnosis a~nd in formul~ating standard therapeutic strategies to prevent and treat ocular complications by studying the types, frequency and dermatological characteristics of each ocular complication in atopic dermatitis. Methods: We evaluated the ocular complications of 4I typical atopic dermatitis patients(26 males, 15 females) who had skin lesion around eyelids or complained of ocular symptoms. Results: Mean age of the patients was 17.7 years. The onset of atopic dermatitis was during infancy in 21 patients, during chiildhood in 15 patients, and during adult in 5 patients and their mean duration of disease was 13.8 years. Mild ocular involvements including blepharitis in 29 patients(58 eyes, 70.7%), keratoconjunctivitis in 29 patients(58 eyes, 70.7%) were seen. More serious com- plications which may lead to decreased visual function including cataracts in 5 patients(10 eyes, 12.1%), retinal detachments in 3 patients(5 eyes, 6.0%) were seen. All the patients who had these two s~erious complications had facial dermatitis. And other ocular invo~lvements including keratoconus in 2 patients(2 eyes, 2.4%), ocular herpes simplex in 1 patient(2 eyes, 2.4%), uveitis in 2 patients(2 eyes, 2.4%) were seen. Conclusion . It is important to perfonn an ophthalmologic examination in the earl~y period of disease in long-standing atopic dermatitis patients especially those who have facial dermatitis for the early diagnosis and treatment of serious sight-threatening complications.