Patterns and Genetic Polymorphisms in Unconjugated Hyperbilirubinemia (Gilbert Syndrome)

Gilbert syndrome is an underdiagnosed clinical entity because >30% of patients are asymptomatic. The clinical and genetic patterns have not been fully elucidated. Several genetic association studies have linked a number of single nucleotide polymorphisms (SNPs) with unconjugated hyperbilirubinemia. We conducted the current study to investigate the different clinical presentations and to validate the association …