Instead of having the function of coagulation factor viii functions multispecific antigen-binding molecule

2011 
Both produced with the coagulation factor IX / activated blood coagulation factor IX and factor X bind specifically, and instead of having a blood coagulation factor VIII cofactor function function, i.e., has a function to promote the activation of Factor X in place of activated blood coagulation factor IX various bispecific antibodies. Among these antibodies, they succeeded in finding the blood coagulation factor VIII in place of high activity function multispecific antigen-binding molecules.
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