Novel presentation of a familial pancreatic cancer syndrome.

Introduction Earlier detection of pancreatic cancer may help identify patients for whom surgical intervention could provide cure or prolong life. In this article, we report the occurrence of breast cancer, melanoma, squamous cell carcinoma of the alveolar ridge, colon cancer, a desmoid tumor of the abdominal wall, and pancreatic adenocarcinoma in a 65-year-old woman. She was identified as having the familial atypical multiple mole melanoma–pancreatic cancer syndrome (FAMMM–PC) with a germline p16 mutation at amino acid position 15.