Th17 and CD24 hi CD27 + regulatory B lymphocytes are biomarkers of response to biologics in rheumatoid arthritis

Sarah Salomon,Caroline Guignant,Pierre Morel,Gauthier Flahaut,Clément Brault,Clément Gourguechon,P. Fardellone,Jean-Pierre Marolleau,Brigitte Gubler,Vincent Goëb

Th17 and CD24 hi CD27 + regulatory B lymphocytes are biomarkers of response to biologics in rheumatoid arthritis

2017

Sarah Salomon
Caroline Guignant
Pierre Morel
Gauthier Flahaut
Clément Brault
Clément Gourguechon
P. Fardellone
Jean-Pierre Marolleau
Brigitte Gubler
Vincent Goëb

Background The aim was to describe the regulatory B and T cells (Breg and Treg) and T helper 17 (Th17) lymphocytes before and under treatment with biologic drugs, and to assess their potential predictive value as biomarkers of response in rheumatoid arthritis (RA).

Keywords:

Diabetes mellitus
Immunology
Abatacept
Lymphocyte
CD24
Rheumatoid arthritis
Rheumatology
Medicine
Regulatory B-Lymphocytes
Internal medicine
Biomarker (medicine)
Prospective cohort study
Rheumatism
Rituximab

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