Additional file 1: Figure S1. of Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient

Constitutive and stimulated expression of Fractalkine/CX3CL1 by human colorectal cancer cell lines. (A) Fractalkine/CX3CL1 mRNA expression in different colorectal cancer cell lines cultured with or without IFN-γ (1000U/ml) and TNF-α (50 ng/ml) for 24 h. (B) Fractalkine/CX3CL1 expression in RKO cells transduced with the cDNA of CX3CL1 (RKO-CX3CL1) or mock-transduced RKO-Mock. (C) Tumor growth of RKO-Mock and RKO-CX3CL1 cells in NSG mice. (JPG 1379 kb)