Asymmetric Total Synthesis of Mycobacterial Diacyl Trehaloses Demonstrates a Role for Lipid Structure in Immunogenicity.

Mira Holzheimer,Josephine F. Reijneveld,Alexandrea K. Ramnarine,Georgios Misiakos,David C. Young,Eri Ishikawa,Tan-Yun Cheng,Sho Yamasaki,D. Branch Moody,Ildiko Van Rhijn,Adriaan J. Minnaard

Asymmetric Total Synthesis of Mycobacterial Diacyl Trehaloses Demonstrates a Role for Lipid Structure in Immunogenicity.

2020

Mira Holzheimer
Josephine F. Reijneveld
Alexandrea K. Ramnarine
Georgios Misiakos
David C. Young
Eri Ishikawa
Tan-Yun Cheng
Sho Yamasaki
D. Branch Moody
Ildiko Van Rhijn
Adriaan J. Minnaard

ABSTRACT: The first asymmetric total synthesis of three structures proposed for mycobacterial diacyl trehaloses, DAT1, DAT2 and DAT3 is reported. The presence of two of these glycolipids, DAT1 and ...

Keywords:

Glycolipid
Immunogenicity
Biology
Biochemistry
Lipid structure
Total synthesis

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations