ИНАКТИВАЦИЯ МЕТИЦИЛЛИНРЕЗИСТЕНТНОГО STAPHYLOCOCCUS AUREUS ИЗЛУЧЕНИЕМ ДИАПАЗОНА 400-470 НМ

Staphylococcus aureus is one of the major reasons for nosocomial infections that often cause post-surgery wound infectious complications. Prevalence in hospitals as well as occurrence in the  community of the clinical isolates of methicillin-resistant  Staphylococcus aureus (MRSA) leave health professionals without  effective means of control over the infection. Complications caused  by MRSA lead to longer hospital stay and higher lethality rates. Due  to the infected wounds treatment issues and high mortality rate it is  important to introduce efficient alternatives to traditional means of  treating and preventing wound infections into the clinical practice of  inpatient surgical units and burn care facilities. It should be hard for bacteria to develop resistance to these treatment methods and measures of preventive care. Antimicrobial action of the 400-470 nm radiation attracts a lot of attention lately. Shortwave visible radiation has distinct advantages over UVC and UVB given the generally acknowledged skin injury risks and risks of development of cancer resulting from the ultraviolet exposure. In comparison with the  photodynamic therapy the 400-470 nm radiation does not require  exogenous photosensitizers with their challenging delivery to a biofilm lying deep within a tissue. Despite research being in its  infancy, in vitro and in vivo studies performed to inactivate clinically  signifi cant isolates of bacteria characterized by antibiotic resistance  suggest that the phototherapy technology using the 400-470 nm  radiation has the potential to treat and prevent surgical and burn  wound infections. In this paper effectiveness of 400-470 nm  radiation for the inactivation of strains of MRSA is analyzed.