Enhancement of optic cup detection from ARGALI using key points

We propose a method for improving the accuracy of the optic cup detected from the ARGALI system. This method makes use of key points from the branching points of large vessels, the analysis of intensity variation and kinks from small vessels to obtain an enhanced optic cup. Measures used to assess the detection of the optic cup showed an 11% and 40% improvement in the mean average overlap and relative area difference respectively over the previous method. The difference in the CDR error was also shown to be reduced to less than 0.1CDR units. The improved optic cup detection is more consistent with the clinical ground truth, facilitating its use in ARGALI for mass screening for glaucoma for early detection to save sight.