THE SYNTHESIS OF MODIFIED D- AND L-ANHYDROHEXITOL NUCLEOSIDES

Abstract The synthesis and antiviral activities of novel L-isomers 9–13 and modified D-guanine analogs 1d,e of recently reported anhydrohexitol nucleosides 1 are described. An efficient approach to known anhydrohexitol nucleoside precursor 2 from diacetone-D-glucose 3 is also reported.