Integrative tumor and immune cell multi-omic analyses to predict melanoma response to immune checkpoint blockade.

Valsamo Anagnostou,Daniel C. Bruhm,Noushin Niknafs,James R. White,John-William Sidhom,Julie E Stein,Hua Ling Tsai,Hao Wang,Zineb Belcaid,Joseph C. Murray,Petra Ross-Macdonald,Megan Wind-Rotolo,Alexander S. Baras,Janis M. Taube,Robert B. Scharpf,Catherine S. Grasso,Antoni Ribas,Drew M. Pardoll,Suzanne L. Topalian,Victor E. Velculescu

Integrative tumor and immune cell multi-omic analyses to predict melanoma response to immune checkpoint blockade.

2020

10009Background: The complex crosstalk between tumor and immune cells during immune checkpoint blockade mandates the development of integrated models to interpret the antitumor immune response and ...

Keywords:

Blockade
Cell
Immune system
Melanoma
Omics
Pathology
Cancer research
Immune checkpoint
Medicine

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