The study of short-term effect for nasopharyngeal carcinoma with the treatment of radiotherapy after interventional chemotherapy

Objective To evaluate the clinical curative effect and methods of external carotid artery perfusion treatment plus radiotherapy for nasopharyngeal carcinoma (NPC). Methods Twenty two patients with nasopharyngeal carcinoma diagnosed by nasopharyngoscopy, CT, MRI were treated by interventional chemotheraphy with riamycin(or epi-adriamycin), 5-fluorouracil and cisplatin (or carboplatin) and followed by radiotherapy. The control group (25 cases) was randomly selected among the patients of nasopharyngeal carcinoma with radiotherapy in our hospital. Results Of all the patients, the total response rate and CR (complete response) were 100% and 90.9%(20/22) for IC group; and 100% and 68.0%(17/25) for control group respectively (P 0.05). Conclusion Radiotherapy combined with transcather arterial chemotherapy have synergic effect on patients with nasopharyngeal carcinoma outcoming with high effectiveness.