Correlation between Microalbuminuria and Atherogenic Index in Evaluating Coronary Vascular Risk in Newly Diagnosed Type 2 Diabetes

Microalbuminuria is a known important risk factor for Kidney disease. Recent studies have highlighted Micro albuminuria as an independent marker for Endothelial dysfunction and Cardiovascular diseases.8 Albumin leakage into urine is a reflection of widespread vascular damage. Microalbuminuria is highly prevalent in patients with Diabetes Mellitus, its prevalence ranging from 10 to 40%. AIM OF THE STUDY: The Aim of the study is to determine the prevalence of Microalbuminuria in newly diagnosed patients with Type 2 Diabetes Mellitus and to compare the effectiveness of Microalbuminuria with the fasting Lipid profile in detecting cardiovascular risk in these patients in terms of Atherogenic Index. MATERIAL AND METHODS: The study group includes 247 patients with Type 2 Diabetes Mellitus. Patients with urinary tract infection, Macro albuminuria, Renal failure and Heart failure are excluded from the study. Fasting and post-prandial blood sugar, Fasting Lipid profile, Atherogenic Index, Creatinine and Urine Albumin are measured in all the patients. The patients were divided in to two groups: Group A, without Microalbuminuria and Group B, with Microalbuminuria. RESULTS: BMI, FBS, PPBS, Total Cholesterol, TGL, Atherogenic Index, Creatinine and Urine Albumin are found to be higher in Group B compared to Group A patients and Serum HDL is found to be lower in Group B compared to Group A patients. Pearson correlation coefficient of Atherogenic Indices with Urine Albumin excretion of Group B patients shows that there is a significant positive correlation (r = 0.60). CONCLUSION: Microalbuminuria can be used as an independent marker for early prediction of cardiovascular complications and can be used as a screening procedure in all patients diagnosed with type 2 Diabetes mellitus.