A New Anti-HIV Triterpene from Geum japonicum

Hong-Xi Xu,Dong-Sheng Ming,Hui Dong,Paul Pui-Hay But

A New Anti-HIV Triterpene from Geum japonicum

2000

Hong-Xi Xu
Dong-Sheng Ming
Hui Dong
Paul Pui-Hay But

Geumonoid (1), a new triterpene, was isolated from Geum japonicum. Its structure was elucidated on the basis of 1D, 2D NMR and MS spectroscopic analysis. Compound 1 showed inhibitory activity against HIV-1 protease.

Keywords:

Protease
Geum japonicum
Triterpene
Triterpenoid
Biochemistry
Biology
Enzyme
Terpenoid
Chemistry
Biological activity
Stereochemistry
Pharmacognosy
Two-dimensional nuclear magnetic resonance spectroscopy

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