Carbamoyl Anion Addition to Azirines.
2021
The addition of carbamoyl anions to azirines affords synthetically useful 2-aziridinyl amide building blocks. The reaction scope was explored with respect to both formamide and azirine, and the addition was found to be highly diastereoselective. A one-pot conversion of a ketoxime to an aziridinyl amide was demonstrated. The method was employed to incorporate an aziridine residue into a dipeptide segment.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
53
References
0
Citations
NaN
KQI