Manganese(II) Chloride

(MnCl2) [7773-01-5] Cl2Mn (MW 125.84) InChI = 1S/2ClH.Mn/h2*1H;/q;;+2/p-2 InChIKey = GLFNIEUTAYBVOC-UHFFFAOYSA-L (MnCl24H2O) [13446-34-9] Cl2H8MnO4 (MW 197.92) InChI = 1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2 InChIKey = CNFDGXZLMLFIJV-UHFFFAOYSA-L (starting material for preparation of organomanganese chloride reagents;1 in combination with RLi or RMgX catalyzes reduction of vinyl and aryl halides,2 stereoselective coupling of vinyl iodides,3 and alkylation of enol triflates;4 also used for Mn–Cu-catalyzed conjugate addition of RMgX to enones5 and for Mn-catalyzed acylation of RMgX by acyl chlorides;6 in combination with NaBH4 is diastereoselective reducing agent;7 starting material for the preparation of Mn enolates regio- and stereo selectively8) Physical Data: anhydrous material: mp 650 °C; bp 1190 °C; d 2.98 g cm−3; hygroscopic. Tetrahydrate: mp 58 °C, d 2.01 g cm−3. Solubility: sol H2O and some polar organic solvents (DMF, NMP, DMPU, etc.); insol hydrocarbons, ether, THF. MnCl2 can be dissolved in THF as its ate complex MnCl4Li2. The latter is easily obtained by mixing LiCl (2 equiv) and anhydrous MnCl2 in THF at rt until dissolution (about 1 h). MnCl4Li2 is generally used in place of MnCl2; it reacts similarly but more rapidly owing to its solubility.1 Form Supplied in: pink grayish powder; widely available. Drying: for organometallic uses, it is recommended that the commercial anhydrous MnCl2 be dried since the industrial anhydrous material contains 0.1–1% H2O. The following procedure is convenient: heating at 200 °C under vacuo (10−2 mmHg) for 2 h. Handling, Storage, and Precautions: anhydrous MnCl2 is a very hygroscopic material. It must be handled very quickly and stored in a tightly closed bottle.