Situation of Antibiotic Use at Miyazaki Medical College Hospital

Recently, transfiguration of infections has been caused by remarkable increase in the amount of antibiotics. We investigated the amount of use and combination of antibiotics during June of 1981, 1982, 1983 and 1984 at our hospital. The results were as follows:1) The total amount of antibiotics use decreased annually. 2) The amount of penicillins, especially carbenicillin and sulbenicillin, decreased remarkably. 3) Of the total combinations, 2-drug combinations occupied 75%-85%. 4) Combination of cephalosporins, especially those of the third generation, and aminoglycosides occurred in the largest number.