Phenolphthalein combination freeze-dried tablet and preparation method thereof

2014 
The invention provides a phenolphthalein combination freeze-dried tablet and a preparation method thereof, and relates to the technical field of medicine and medicine production. The phenolphthalein combination freeze-dried tablet comprises phenolphthalein, starch and cane sugar. The preparation method comprises the following steps: adopting starch and cane sugar as auxiliary materials; carrying out heating treatment on ordinary cornstarch, so as to improve the bonding and disintegrating effect of starch in the tablet and improve the formability of the tablet, wherein the phenolphthalein combination freeze-dried tablet just needs two kinds of auxiliary materials, namely starch and cane sugar. The phenolphthalein combination freeze-dried tablet adopts the twice-dropping and twice-rising freeze-drying process, twice dropping of temperature and twice rising of temperature can facilitate better formability, the dissolvability of the tablet is improved, and the biological availability of the tablet is improved; the tablet overcomes the defects of the ordinary phenolphthalein tablet, the category and dosage of auxiliary materials in the phenolphthalein tablet are reduced, and the phenolphthalein combination freeze-dried tablet is high in dissolvability and high in biological availability, and guarantees the curative effect and safety of clinical medication.
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