Prognostic significance of MGMT promoter methylation in diffuse glioma patients

Nikola Jovanović,Tatjana Mitrović,Vladimir J. Cvetković,Svetlana Tošić,Jelena Vitorović,Slaviša Stamenković,Vesna Nikolov,Aleksandar Kostić,Nataša Vidović,Tatjana Jevtovic-Stoimenov,Dusica Pavlovic

Prognostic significance of MGMT promoter methylation in diffuse glioma patients

2019

Nikola Jovanović
Tatjana Mitrović
Vladimir J. Cvetković
Svetlana Tošić
Jelena Vitorović
Slaviša Stamenković
Vesna Nikolov
Aleksandar Kostić
Nataša Vidović
Tatjana Jevtovic-Stoimenov
Dusica Pavlovic

AbstractCurrent treatment options for diffuse glioma patients include maximum safe resection followed by a combination of radiation therapy and chemotherapy with alkylating agents. The DNA-repair e...

Keywords:

Methylation
Biochemistry
Cancer research
Biology
Diffuse Glioma
overall survival
treatment options
mgmt promoter methylation
CpG site
Radiation therapy
Resection
Chemotherapy

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