Dermatosis por IgA lineal vinculada a fármacos

La dermatosis por IgA lineal (DAL) es una enfermedad ampollar poco frecuente, autoinmunitaria y de caracter adquirido. Puede ser idiopatica (DALI), inducida por farmacos (DALIF) o asociarse a otras entidades. La DALIF tiene particularidades clinicas que permiten sospechar la vinculacion a farmacos, como la presencia del signo de Nikolsky positivo, extensas areas de piel denudada y poca frecuencia de compromiso mucoso. Presentamos el caso de una paciente de 75 anos con diagnostico de DAL y clinica evocadora de DALIF. Palabras clave: dermatosis por IgA lineal, farmacos, compromiso palmar. Dermatol. Argent. 2017, 23 (1):42-45 Drug-induced linear IgA bullous dermatosis Abstract Linear IgA dermatosis is an acquired autoimmune rare bullous disease. It can be idiopathic (DALI), drug-induced (DALBD) or associated with other entities. DALBD has clinical features that allow us to suspect linking to drugs such as the presence of positive Nikolsky sign, large areas of denuded skin and infrequency of mucosal involvement. We present a 75 years old woman diagnosed with DAL with evocative DALBD clinic. Key words: linear IgA bullous dermatosis, drugs, palmar involvement. Dermatol. Argent. 2017, 23 (1):42-45