Experimental Design in the Analysis of Interferential Effects for the Determination of Rubidium in Chloride-type Brine by Atomic Absorption Spectrometry Technique

Experimental design (DOE) was employed to precisely determine the content of rubidium in chloride type brine of Qionglai (A city in Sichuan province, southwest of China) using atomic absorption spectrometry (AAS) technique. From the statistical analysis of six factors, it was found that K+ and Cl− were the significant interfering elements for the determination of rubidium. A model was established to eliminate the interference effects of K+ and Cl−. The experimental results indicate that, under the optimal conditions, the developed method for the rubidium determination possesses the advantages of low detection limit (0.019 µg·mL−1 at a significant level of 0.05) and higher recovery (97.2%–103.4%).