اندازه¬گیری شاخص¬های تنفسی در جمعیت¬های نمونه مناطق مختلف ایران و تعیین معادله های مرجع به منظور برآورد این شاخص ها در افراد ایرانی

Introduction : Normal values of cardio-pulmonary and hematic parameters are not the same in different populations rather these reference values are influenced by a variety of factors including age, gender, genetics and geographical region of living. The aim of this study was to identify the physiological values of pulmonary system in Iranian adult population and obtain the reference equations for these parameters. Methods: Sample subjects were randomly selected from cities in different regions of the country. Having been identified, the healthy individuals were sent to laboratory. There, vital pulmonary parameters including tidal volume, forced vital capacity, slow vital capacity, respiratory rate and forced expiration volume were separately measured in men and women using standard methods and devices by expert researchers observing bioethics. Laboratory conditions were the same for all people, in sedentary position and after rest. Results: The obtained results were classified for different age groups of men and women. Applying regression formulas, mean values for different age groups were calculated and then reference equations were derived for each parameter as below: TV= -0.035+0.031(sex)+0.003(height), FEV1= -0.651-0.004(age)+0.020(height), RR= 44.791-0.033(age)-0.108(height)-0.035(weight), SVC= -0.424+0.019(height), FVC= 0.842+0.083(sex)+0.010 (height) +0.003(weight). Conclusion: Regarding the obtained reference equations for healthy Iranian population, one can calculate and predict pulmonary parameters for an individual using his/her personal features such as age, sex, height and weight. In other words, the mean value of each parameter provides the appropriate standard for that individual. Therefore, these values are criteria for normality or abnormality of the measured parameters in that individual.