Clinical and Histological Prognostic Factors for Local Recurrence and Metastasis of Cutaneous Squamous Cell Carcinoma: Analysis of a Defined Population

Cutaneous squamous cell carcinomas (cSCC) can recur locally and can metastasize. The objective of this study was to identify clinical and histopathological prognostic factors for local recurrence and metastasis in cSCCs at any body site. Clinical and histopathological data were collected from 224 patients with cSCC. During the me-dian follow-up period of 43 months (range 0–73 months) the cumulative probabilities of recurrence-free survival at 1, 2 and 4 years post-treatment were 98.0%, 96.9% and 94.7%, respectively, and for metastasis-free survi-val 98.1%, 97.0% and 95.9%, respectively. In univariate