COMORBIDITY IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: THE ROLE OF HYPERAMMONEMIA

Chronic obstructive pulmonary disease (COPD) is characterized by comorbidity. Obesity is one of the comorbidity in COPD. Obesity, in turn, causes the liver metabolic damage, such us non-alcoholic fatty liver disease (NAFLD) with a decrease of detoxification function, the conversion of toxic ammonia to urea and the development of hyperammonemia. The aim of the study is to identify hyperammonemia in patients with COPD and obesity, to analyze the degree of its effect on disease course and the quality of life.