Noncancer Disease Incidence in Atomic Bomb Survivors, 1958–1998

Abstract Yamada, M., Wong, F. L., Fujiwara, S., Akahoshi, M. and Suzuki, G. Noncancer Disease Incidence in the Atomic Bomb Survivors, 1958–1998. Radiat. Res. 161, 622–632 (2004). We examined the relationships between the incidence of noncancer diseases and atomic bomb radiation dose using the longitudinal data for about 10,000 Adult Health Study (AHS) participants during 1958–1998. The current report updates the analysis we presented in 1993 with 12 additional years of follow-up. In addition to the statistically significant positive linear dose–response relationships detected previously for the incidence of thyroid disease (P < 0.0001), chronic liver disease and cirrhosis (P = 0.001), and uterine myoma (P < 0.00001), we also found a significant positive dose response for cataract (P = 0.026), a negative linear dose–response relationship for glaucoma (P = 0.025), and significant quadratic dose–response relationships for hypertension (P = 0.028) and for myocardial infarction among survivors exposed at less ...