Research Article PHYTOCHEMICAL INVESTIGATION AND CYTOTOXIC ACTIVITY OF METHANOLIC EXTRACT OF ALPINIA GALANGA

Phytochemical investigation of methanol extract of seeds of the Alpinia galanga led to the isolation of one new diterpenoid, along with three known compounds. Their structures were established on the basis of NMR and mass spectroscopic analysis. In addition, all the isolates were tested for their cytotoxicity against lung cancer (H522), leukemia K562, breast cancer (MCF-7/ADR) and prostate cancer (DU145) cancerous cell lines. The new Compound 1 has shown good cytotoxic activity.