Research data supporting "Sigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1"

Atomic force microscopy (AFM) analyses of interactions between the sigma-1 receptor (σ1R), STIM1 and Orai1 isolated from the plasma membrane. Data include: 1. AFM images of Orai1 isolated with σ1R and STIM1, showing the Orai1 channel decorated by either STIM1 or both STIM1 and σ1R. 2. Frequency distributions of the volumes of the decorated Orai1 particles, bound peripheral particles (STIM1) from cells expressing Orai1 and STIM1, and bound peripheral particles (σ1R and STIM1) from cells expressing Orai1, STIM1 and σ1R. 3. AFM images showing strings of STIM1 connecting several Orai1 channels.