Catfish (Clarias gariepinus) Biscuit and Oil Supplementation and its Effect on Lipid Profile, Oxidative Stress Markers and Cognitive Function of the Elderly

Cognitive impairment is a classic problem among the elderly. One of the risk factors of cognitive decline is the high levels of lipid profile. Deep-sea fish oil has been studied, and it has beneficial effect for improving lipid profiles. However, no studies have evaluated the beneficial effects of freshwater fish oil for improving lipid profiles. Catfish biscuit and oil supplementation is expected to improve the level of lipid profiles and maintain cognitive function of the elderly. We used a pre-post, single-blinded, randomized controlled trial (RCT) design. A total of 67 subjects with dyslipidemia aged 45-74 years were randomly selected and divided into four groups, as follows: Placebo (P); Catfish Biscuit (CB); Catfish Oil (CO); and Catfish Biscuit and Catfish Oil (CBCO). The intervention was conducted for 60 days (January