The relation between objective and subjective impairment in cognitive function among multiple sclerosis patients - the role of depression
2001
Objective: To evaluate the relations between perceived cognitive function and objective cognitive deficit and to assess variables affecting perceived cognitive function among multiple sclerosis (MS) patients. Methods: A cross sectional study of patients with MS. All patients were interviewed and the Expanded Disability Status Scale (EDSS) score was determined. The dependent variables were four items assessing perceived concentration and thinking, attention, memory, and whether others have noticed memory or concentration problems. The explanatory variables were age, sex, duration of disease, number of relapses in the last 2 years, EDSS score, depressive symptoms score (CES-D) and the domains of the Neurobehavioral Cognitive Status Examination (NCSE) assessing cognitive performance. Bivariate and then multivariate analysis were performed. Results: One hundred and sixty-one MS patients were included. Mean age was 44.2 years (s.d. 11.3 years), mean EDSS score was 4.86 (s.d. 1.93). Seventy-two per cent of the ...
Keywords:
- Physical therapy
- Expanded Disability Status Scale
- Effects of sleep deprivation on cognitive performance
- Multivariate analysis
- Cognitive skill
- Cognition
- Cognitive deficit
- Medicine
- Cross-sectional study
- Cognitive disorder
- Developmental psychology
- Clinical psychology
- Central nervous system disease
- Multiple sclerosis
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