Rare solitary fibrous tumor of the stomach: A case report.
2015
Introduction. Solitary fibrous tumors are rare soft tissue tumors of
submesothelial origin and variable malignant potential. The most common
localization is pleural, whereas only 0.6% are of extrapleural localization.
Solitary fibrous tumor of the peritoneum, especially of gastric serosa is an
extremely rare form of this tumor. Case report. We presented a 65- year-old
female patient with solitary fibrous tumor of the stomach. Histopathological
analysis of removed tissue showed the presence of tumor tissue built of
spindle cells, elongated nuclei with moderately abundant cytoplasm. Cells
were in a noncohesive arrangement, in smaller areas distributed in the form
of palisade. There were amounts of hipocellular connective tissue,
hyalinised, with small foci of dystrophic calcification. Mitoses were rare
(less than 3/10 HPF). Blood vessels surrounded the connective tissue.
Reviewed material did not contain elements of the parent organ.
Immunohistochemically there were positivity on CD34 and vimentin, and
negativity to S100, SMA, CD117, dezmin, and Ki-67 is < 2%. The change was
diagnosed as a solitary fibrous tumor. Conclusion. Considering that benign
solitary fibrous tumors of extrathoracic localizations are extremely rare
neoplasms with unpredictable biological behavior and the possibility of
recurrence, a long-term clinical and endoscopic follow-up on yearly basis of
patients with this disease is recommended.
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