Influence of various ways of rehabilitation on functional and immunological indicators of the organism of materials of maturity aged by an extreme injury.

2020 
The purpose of the study is to study the effect of various methods of rehabilitation after a fracture of the radius in a typical location on the heart rate variability and the state of innate immunity factors, the content of IL-1, -2, -4, -6, -8, -10 in elderly women. In 50 women at the age of 63,5±1,5 years, the indicators of the spectral analysis of the heart rhythm were studied on the 3, 7, 14 days of rehabilitation procedures. The state of the cellular factors of innate immunity was assessed by the phagocytic activity and oxygen-dependent metabolism of neutrophilic granulocytes in the nitric blue tetrazolium reduction test. The cytokine status included the determination of IL-1, -2, -4, -6, -8, -10 by enzyme immunoassay. For the statistical analysis, the Shapiro-Wilks test, one-sided Fisher's exact test, and Student's t test were calculated. It has been shown that the influence of rehabilitation measures using the method of post-isometric muscle relaxation decreases the heart rate variability of elderly women, restores the balance between the sympathetic and parasympathetic parts of the autonomic nervous system, normalizes the functional and metabolic status of neutrophilic granulocytes and Th1/Th2 lymphocytes. The results obtained allow us to recommend the inclusion of the method of post-isometric muscle relaxation in the complex of rehabilitation measures for fractures of the radius in a typical place.
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