Bioconcentration and excretion of benthiocarb and simetryne by carp

Abstract Bioconcentration and excretion of benthiocarb(S- p -chlorobenzyl N , N -diethylthiocarbamate) and simetryne [2,4-bis(ethylamino)-6-methylthio-1,3,5-triazine)] were studied for carp ( Cyprinus carpio L.). The concentrations of both chemicals in muscle and viscera of carp reached plateaus after 12 h exposure. Bioconcentration factors (BCF) of benthiocarb were 25.5 in muscle, 62.7 in liver, 72.7 in kidney and 63.3 (mean, n = 4) in gallbladder over the 168 h exposure period. Similarly, BCF of simetryne were 2.4 in muscle, 13.5 in liver, 8.1 in kidney and 10.9 in gallbladder over the 72 h exposure period. The excretion rate constants of benthiocarb were 0.10 h −1 for muscle, 0.09 h −1 for liver, 0.13 h −1 for kidney and 0.09 h −1 for gallbladder assuming their processes to be first-order kinetics. Similarly, those of simetryne were 0.44 h −1 for muscle, 0.37 h −1 for liver, 0.29 h −1 for kidney and 0.23 h −1 for gallbladder.