Поиск клинико-генетических ассоциаций при алкогольной болезни печени

It is established that an increased risk of icteric forms of alcoholic hepatitis is associated with combinations of genotypes C1C1/del genes CYP2E1/GSTT1 and genotypes C1C1/CT genes CYP2E1/XRCC3. Severe alcoholic hepatitis accompanied by hepatic encephalopathy, occurs much more frequently in carriers of genotypes C1C1/GA genes CYP2E1/TNFA.