The p16/Cdkn2a/Ink4a Gene Is Frequently Deleted in Nitrosourea-Induced Rat Glial Tumors

Jürgen Schlegel,Guido Piontek,Michael Kersting,Marcus Schuermann,Roland Kappler,Harry Scherthan,Christopher M. Weghorst,Gregory S. Buzard,Hans-Dieter Mennel

The p16/Cdkn2a/Ink4a Gene Is Frequently Deleted in Nitrosourea-Induced Rat Glial Tumors

1999

Jürgen Schlegel
Guido Piontek
Michael Kersting
Marcus Schuermann
Roland Kappler
Harry Scherthan
Christopher M. Weghorst
Gregory S. Buzard
Hans-Dieter Mennel

The present study investigates nitrosourea-induced rat (Rattus norvegicus) glioma cell lines for the functional status of the p16/Cdkn2a/Ink4a gene, which encodes

Keywords:

Comparative genomic hybridization
Glioma
Biology
Cell cycle
Nitrosourea
Genetic enhancement
Gene
CDKN2A
Cell culture
Molecular biology
p16 cdkn2a
functional status

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