Klebsiella pneumoniae Sequence Type 258 First Outbreak of KPC-2-Producing

isolates from three patients admitted to the neu-rosurgery (NS) department in an 870-bed teaching hospital inSouthKoreaovera5-weekperiod.Allthreepatientswereadmit-ted for the treatment of central nervous system (CNS) lesions.One patient underwent craniotomy for the resection of a CNStumor,andtwopatientsreceivedcatheterinsertionsforintracra-nial hemorrhage. For postoperative care, these patients were ad-mittedtotheneurosurgicalintensivecareunit(ICU)from2to49days. The patients received mechanical ventilation. The periodsspentbytwopatientsintheICUoverlapped.Afteracutemanage-ment, all three patients were transferred to the same NS generalward. On 12 July 2011, the first non-carbapenem-susceptible